Harvard University’s core scientific facilities provide faculty, researchers, and students with an array of specialized equipment, technologies, and services to support innovative research. Twenty different cores operate under the Division of Science. These cores offer a wide variety of services and instruments. Fees, access, and required training vary by core.
Offers access to 20 different high-powered imaging microscopes. Registration and laser safety training is required for all users.
Faculty Director: Jeff Lichtman
Offers access to high throughput “next generation” sequencing using Illumina technology and capillary-style Sanger sequencing. The core offers training, support, and fee-for-service work and provides access to ancillary equipment for sample preparation.
Faculty Director: Gonzalo Giribet
Offers access to several cytometers for experiments, training and other services.
Faculty Director: Andrew Murray
Offers access to instruments for analyzing, creating, and processing microarrays.
Offers access to instrumentation used for protein characterization and quantitation in the context of systems biology. The core offers numerous services, from protein identification to C-terminal sequence analysis to intact protein molecular weight determination by ESI.
Offers access to electrospray, and MALDI-TOF mass spectrometers. A range of complete mass spectrometry services are available including intact protein MW measurement, MALDI-TOF (proteins, polymers, oligosaccharides etc.), targeted and untargeted LC-MS omics profiling, SRM quantification of drugs/metabolites, and much more.
Faculty Director: Matthew Shair
Offers access to bioinformatics analysis services for all users of the Core Sequencing facility and FAS faculty groups regardless of the origin of their data.
Director: Michele Clamp
Offers access to instruments for liquid handling, thermal cycling, and many other instruments.
Faculty Director: Michael Desai
Offers access to transgene microinjection, embryonic stem cell gene targeting, blastocyst injection, cryopreservation, strain rederivation, and EUCOMM/KOMP.
Faculty Director: Josh Sanes
Offers access to services and instrumentation that facilitate the derivation and distribution of iPS cell lines. The core houses iPS cells produced by HSCI scientists, and it functions as a laboratory to produce disease-specific lines.
Offers access to the X-ray diffraction facility. The facility provides researchers with single crystal X-ray data collection, structure solution, and refinement of small molecule structures.
Faculty Director: Theodore Betley
Offers access to nine different spectrometers.
Faculty Director: Matthew Shair
Offers cutting edge computational support and consultation. With more than 12,000 processing cores and numerous software modules and applications, Research Computing provides researchers the necessary tools for large-scale computing.
A “build and test” laboratory facility supporting: cleanroom fabrication and characterization of nanoscale devices and structures; electron-beam imaging and analysis tools; materials characterization including XPS, microCT, PL, FTIR, AFM, microfluidic processing and a cell culture and microscopy facility.
Helium Liquefaction & Recovery Core
Offers Helium liquefaction and recovery services to laboratories.
Faculty Director: Gerald Gabrielse
Offers graphic design support and training.
Offers machine shop training and classes.
Go here for a complete listing of all cores across Harvard (not just under the Division of Science).